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Jan 2023, Vol 11, Issue 1
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Original Article
Association Between Amniotic Fluid Lactate Concentration and Labor Outcome in Primiparas’ Deliveries
Fatemeh Bahadori, Leila Majdi, Reza Hajizadeh, Ali Soleimany, Hamid Reza Khalkhali
Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran

DOI: 10.15296/ijwhr.2022.xx
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Keywords : Amniotic fluid lactate level, Labor, Outcome, Cesarean delivery
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Abstract
Objectives: Because of the higher frequency of dystocic labor in nulliparous pregnant women, a supplementary test is highly important for predicting the probability of the cesarean intervention. The aim of this study was to evaluate the correlation between the amniotic fluid lactate (AFL) level and the outcome of delivery in nulliparous term pregnant women referring with the complaint of the spontaneous rupture of membranes.

Methods: Nulliparous women with term pregnancies and single cephalic presentation, presenting with the spontaneous rupture of membranes and active phase of labor, were enrolled in this study. The AFL was evaluated by a portable device. In addition, the partogram curve, labor progression, and delivery method were recorded for each patient. Finally, the association between the need for cesarean delivery and the AFL level was investigated as well.

Results: In general, 200 nulliparous pregnant women were enrolled in this study. The mean age of women and the mean AFL were 29.12 ± 7.54 years and 7.32 ± 3.63 mmol/L, respectively. Among 144 patients with AFL below 10.1 mmol/L, 33 patients (22.9%) had a cesarean delivery. Further, among 56 patients with AFL above 10.1 mmol/L, 42 patients (75%) had a cesarean delivery (P < 0.001). Eventually, an AFL level higher than 10.1 mmol/L in predicting the cesarean section had a sensitivity of 85.6% and a specificity of 82.7%.

Conclusions: Amniotic lactate levels >10.1 mmol/L in nulliparous women with single-term pregnancy can be used as a marker for predicting cesarean delivery.

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