Materials and Methods: This study is a sectional one which was done on 322 infertile couples referring to the infertility center at Alzahra Hospital in Tabriz. Sampling method was available. The gathering data instruments included social-individual particulars questionnaire and perceived stress scale questionnaire (PSS) which was completed as self-completion by the participants. The multivariate linear regression analysis method was used for defining the social-individual predictors of perceived stress.

Results: The findings of the research showed that mean (standard deviation) of perceived stress among women was 27.4 (6.0[H1] ) and 25.9 (5.3) among men out of 0-56 grade range and there was statistically significant difference between men and women due to perceived stress (P<0.001). The[H2] variable of monthly income sufficiency for living expenses, occupation, type of current treatment, Method of treatment, Etiology of infertility, methods of contraception were the predictors of perceived stress.

Conclusion: The results of this research showed higher perceived stress among women compared to men; therefore it is necessary to provide approaches for reducing the perceived stress focusing on its predictive variables for recovering the couples' mental status.