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Jan 2023, Vol 11, Issue 1
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Case Report
Is There any Effect of COVID-19 on Follicular Environment in Women Underwent ART?
Nafiye Yılmaz1, Zehra Kurdoglu2, Caner Özer3, Sibel Aydogan4, Özlem Moraloglu Tekin1
1Department of ART, Gulhane Medical Faculty, University of Health Sciences Turkey, Ankara City Hospital, Ankara, Turkey
2Department of Obstetrics and Gynecology subdivision of ART, Faculty of Medicine, Ankara Yildirim Beyazıt University, Ankara City Hospital, Ankara, Turkey
3Department of Histology and Embryology, Ankara City Hospital, Ankara, Turkey
4Department of Microbiology, Ankara City Hospital, Ankara, Turkey

DOI: 10.15296/ijwhr.2022.xx
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Keywords : SARS-COV-2, In vitro fertilization, Oocyte retrieval, Follicular fluid, Embryo culture medium
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Abstract
There is insufficient data on the impact of severe acute respiratory coronavirus-2 (SARS-CoV-2) on the reproductive tissues, its possible risk of cross-contamination, transmission and adverse effect on in vitro fertilization (IVF) outcome. Until today, there is no report associated with viral RNA in both follicular fluid and embryo culture medium from SARS-COV-2 positive women. In this case report, a 24-year-old woman with SARS-CoV-2 was presented. We investigated the SARS-COV-2 positivity in the follicular fluid and embryo culture medium of mildly symptomatic woman on oocyte pick up (OPU) day. We could not detect viral RNA in neither the follicular fluid nor the embryo culture medium. In addition, although the response of ovarian stimulation was normal, the number and maturity of the retrieved oocytes were low.

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