|L-Citrulline Level in Pregnant Adolescent With Severe Preeclampsia Compared to Without Preeclampsia: A Cross-sectional Study|
|Dini Hidayat, Tri Mulya Fitriasari, Tono Djuwantono, Yudi Mulyana Hidayat, Setyorini Irianti, Mulyanusa A Ritonga, Sunardi Sunardi|
|Department of Obstetrics and Gynecology, Faculty of Medicine Padjadjaran University/Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia|
IJWHR 2022; 10: 011-015
Viewed : 492 times
Downloaded : 682 times.
Keywords : Severe preeclampsia, L-citrulline, Nitric oxide
|Full Text(PDF) | Related Articles|
Objectives: Numerous studies have been performed on the effect of L-arginine supplementation on improving maternal outcomes, but studies on the impact of L-citrulline in pregnancy are limited. This study aimed to evaluate the L-citrulline level in pregnant adolescents with severe preeclampsia compared to those without preeclampsia.
Materials and Methods: This is a cross-sectional study among 60 adolescent pregnant women giving birth in the Emergency Room and Delivery Room in Hasan Sadikin Hospital, Bandung, Indonesia from May to October 2020. The L-citrulline levels were examined in women with severe preeclampsia (n = 30) and those without preeclampsia (n = 30).
Results: The L-citrulline level in adolescent pregnancies with severe preeclampsia was lower than those without preeclampsia (79.7±40.4, 122.3±61.9 pg/mL, respectively and P = 0.003). But no correlations were observed between L-citrulline levels with systolic blood pressure, diastolic blood pressure, and mean arterial pressure (MAP).
Conclusions: There was a difference in serum L-citrulline level of adolescent pregnancies with severe preeclampsia and without pre-eclampsia.
Cite By, Google Scholar