International Journal of Women's Health and Reproduction Sciences

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Apr 2017, Vol 5, Issue 2

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Original Article
Investigating the Success Rate of Sex Selection in Cycles of Intrauterine Insemination of Sperm Using an Albumin Gradient Method in Infertile Couples Referring to the Omid Persian Gulf Infertility Center of Bushehr, Iran
Shahnaz Ahmadi¹, Elham Rahmani², Niloofar Motamed^3,4, Fatemeh Sadeghi⁵
¹Associate Professor, Department of Gynecologic Obstetric. Iran University of Medical Sciences, Tehran. Iran ²Associate Professor, Department of Gynecologic Obstetric, Bushehr University of Medical Sciences, Bushehr, Iran ³Department of Community Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran ⁴The Persian Gulf Nuclear Medicine Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran ⁵Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran
IJWHR 2017; 5: 107-111 DOI: 10.15296/ijwhr.2017.20 Viewed : 4298 times Downloaded : 9594 times. Keywords : Infertility, Insemination, Sex preselection, Spermatozoa
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Abstract

Objectives: Sex selection is an important concern for some couples. One of the relatively more simple and inexpensive methods, which does not need to use toxic chemicals to separate the Y and X sperms, is the Ericsson method. Therefore, the aim of this study is to evaluate the results of sex selection in infertile couples by using the albumin gradient method. Materials and Methods: The present study is a quasi-experimental clinical trial study, conducted on 80 infertile couples. After the induction of ovulation and a vaginal sonography, sperm samples were prepared using the albumin gradient method, after which intrauterine insemination (IUI) was conducted. The rate of successful sex selection was then calculated. Results: Among 80 cases of performed IUI, 22 cases (27.5%) were successful, among which 3 cases (8.3%) suffered miscarriages and 19 cases (23.7%) were associated with a successful pregnancy. The success rate of sex selection was 59.1% in successful pregnancies. In general, the sex selection success rate was higher for the male gender; as a result, the success rates in 68 requests for male sex and 12 requests for female sex totaled 12 cases (17.6 %) and 1 case (3.8%), respectively. Conclusion: Albumin gradient is an appropriate sex determination method in IUI cycles due to a 23.7% chance of pregnancy in infertile women, while the success rate is 59.1% in sex determination.