International Journal of Women's Health and Reproduction Sciences

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Apr 2024, Vol 12, Issue 2

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Case Report
Successful Surgical Procedure of Vaginal Cancer Located at the Mid Portion of the Vagina: A Case Report
Soheila Aminimoghaddam, Setare Nassiri, Maedeh Barahman, Elham Hemmatyar, Nahid Hemmatyar
Iran University of Medical Sciences, Tehran, Iran
DOI: 10.15296/ijwhr.2023.48 Viewed : 3474 times Downloaded : 2450 times. Keywords : Vaginal cancer, Situs inversus, Radiotherapy
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Abstract

Introduction: Vaginal cancer is extremely uncommon and most types of this cancer are secondary from other sites such as the cervix or uterine endometrium. Due to the rarity of this gynecologic cancer, studies are limited about treatment modality and most of them have recommended pelvic and vaginal radiotherapy rather than radical surgery. Combined modality including surgery and adjuvant radiotherapy is not supported by experts because of high rates of morbidities. The purpose of our report was to declare the effectiveness of radical surgery in vaginal cancer located in the mid-portion of the vagina, where radiotherapy is considered as the standard treatment. Case Presentation: A woman with vaginal primary squamous cell carcinoma (SCC) in the mid-portion of the vaginal wall undergoing a radical surgery was evaluated in this study. All margins were free of tumoral involvement. In addition, our patient had situs inversus as a rare congenital anomaly which was detected accidentally during the imaging study. Conclusions: Severe and irreversible fibrosis of the vagina after radiotherapy is known as a major challenge, especially in younger patients while shortening of the vagina after surgery is reversible although achieving free tumor margin is absolutely critical. Therefore, an important question arises regarding vaginal cancer whether the advantages of every modality outweigh the disadvantages or not. Thus, it is recommended that surgery is an alternative for radiation by means of a team with high experience in surgery even in vaginal cancer located at the mid portion.