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May 2014, Vol 2, Issue 3
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Original Article
Preventive Analgesia with Intravenous Paracetamol for Post-cesarean section Pain Control
Simin Atashkhoyi1, Sousan Rasouli1, Zahra Fardiazar2, Morteza Ghojazadeh3, Pouya Hatami Marandi4
1Associate Professor of Anesthesiology, Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2Professor of Obstetrics & Gynecology, Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3Associate Professor of Physiology, Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4Medicine Student, Tabriz University of Medical Sciences, Tabriz, Iran

IJWHR 2014; 2: 131-137
DOI: 10.15296/ijwhr.2014.20
Viewed : 1720 times
Downloaded : 1960 times.

Keywords : Cesarean section, Paracetamol, Postoperative pain, Preventive analgesia
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Abstract
Objectives: Effective pain therapy after cesarean section is essential for parturient comfort and to allow early ambulation to facilitate care of her infant. This study evaluated the analgesic effect of preventive 1gr intravenous paracetamol on postoperative pain and analgesic consumption during the 24 hours after cesarean section.

Materials and Methods: One-hundred American Society of Anesthesiologists (ASA) I or II status parturient scheduled for elective cesarean section under spinal anesthesia. Patients received 1gr iv paracetamol into 100 ml normal saline (study group; n=50) or normal saline alone (placebo group; n=50) 20 minutes before the end of operation.

Results: Pain scores were lower in the study group in the Post anesthesia care unit (PACU) (p<0.001) and up to 4h after operation (p<0.001). Cumulative analgesic consumption was lower in the study group (p<0.001).

Conclusion: Preventive administration of 1gr iv paracetamol reduces the intensity of pain in the PACU and until 4h after operation and analgesic consumption following cesarean section.

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