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Oct 2019, Vol 7, Issue 4
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Original Article
Role of Maternal Serum Glycodelin as Predictor of Ectopic Pregnancy in First Trimester
Wasan Wajdi Ibrahim1, Afraa Mahjoob Al-Naddawi1, Hayder A. Fawzi2
1Department of Obstetrics and Gynaecology, College of Medicine / Baghdad University, Iraq
2Department of Clinical Pharmacy‎, Baghdad Medical hospital, Ministry of Health, Baghdad, Iraq‎

IJWHR 2019; 7: 467–470
DOI: 10.15296/ijwhr.2019.77
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Keywords : Abdominal pain, Ectopic pregnancy, Glycodelin, Vaginal bleeding
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Abstract

Objectives: Assessment of glycodelin (GD) as a marker for unruptured ectopic pregnancy (EP) in the first trimester of pregnancy.

Materials and Methods:This case-control study was conducted during June 2016 to May 2017 in the Obstetrics and Gynecological Department of Baghdad University at Baghdad teaching hospital/medical city complex. In this study, 100 pregnant women in their first trimester of pregnancy were included after clinical and ultrasonic findings.

Results: Based on the results, GD levels in EP were significantly lower than those with normal intrauterine pregnancy (1.58 ± 1.18 vs. 30.1 ± 11.9). In addition, using receiver operator curve analysis, the cut-off GD level of 9.5 and less had acceptable validity results (100% sensitivity, 100% specificity, 95% positive predictive value, 100% negative predictive value, and accuracy 100%) to predict EP.

Conclusions:In general, serum GD is considered as an excellent predictor of unruptured EP.

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