|Comparative Investigation of the Sensitivity of Candida Fungi Isolated From Vulvovaginal Candidiasis to Nystatin and Teucrium polium Smoke Product|
|Marzieh Akbarzdeh1, Batool Bonyadpour2, Kayvan Pakshir34, Abdol Ali Mohagheghzadeh4|
|1Maternal-fetal Medicine Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences. Shiraz, Iran
2Department of Midwifery, Islamic Azad University, Shahr-e-Babak Branch, Iran
3Department of Parasitology and Mycology, Central Basic Research in Infectious Diseases, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
IJWHR 2019; 7: 508-514
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Keywords : Vulvovaginal candidiasis, Albicans, Nystatin, Teucrium Polium, Smoke, Persian medicine
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Objectives: The present study aimed to compare the antifungal activities of Teucrium Polium smoke product and nystatin in the treatment of Candida vaginitis in vitro.
Materials and Methods: In this quasi-experimental study, 105 subjects were diagnosed with Candida vaginitis. The data were collected through a collection form and the species were isolated by the germ tube, as well as CHROMagar chromogenic and chlamydospore formation tests.
Results: Based on the results of the germ tube, chlamydospore formation, and CHROMagar tests, 70.5%, 23.8%, and 66.6% of the species were Candida albicans, respectively. In addition, 99% of the samples were sensitive to nystatin. A significant relationship was also observed between the antifungal drug and the type of organism (P<0.02). Finally, all the 15 standard clinical samples were sensitive to T. polium smoke.
Conclusions: In general, the results confirmed the antifungal effects of T. polium and nystatin on the species isolated from 10 clinical samples obtained from Candida vaginitis as well as on five standard strains.
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