|The Serum Level of Vitamin D in Women with Urinary Incontinence due to Pelvic Floor Disorder and Prolapse; A Regional Case-control Study on Iranian Population|
|Shahnaz Barat1, Zinatossadat Bouzari1,2, ShabnamMehdinia3, Karimollah Hajian-Tilaki4, Mojgan Neimi Rad5|
|1Department of Obstetrics &Gynecology ,Fateme Zahra Fertility & Infertility Research Health Center, Babol University of Medical Science, Babol, Iran
2Department of Obstetrics &Gynecology ,Cellular & Molecular Biology Research Center, Babol University of Medical sciences, Babol Iran
3Committee of Research, Babol University of Medical Sciences, Babol, Iran
4,Department of Biostatics and Epidemiology,Non-Communicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran
5 Committee ofResearch, Babol University of Medical Sciences, Babol, Iran
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Keywords : Pelvic Floor Disorders, Vitamin D, Urinary Incontinence, Women
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Objectives:Vitamin D is important for the muscular tone and bone metabolism.Due to the high prevalence of vitamin D deficiency in Iranian women, we aimed to investigate the difference in vitamin D levels between patients with and without pelvic floor disorder (PFD)to assess the possible effect of vitamin Don PFD.
Methods:The present case-control study investigated 209 women referring to Ayatollah Rouhani Hospital,Babol, Iran, in 2017. Patients were examined for prolapse and those with at least one disorder were categorized as the case group (N=104) and patients without PFD as the control group (N=105). The serum level of 25-hydroxyvitamin D was compared between groups.
Results:Mean patients’ age and abdominal circumference were significantly higher in the case group (P<0.001 and P=0.046, respectively). The total mean±SD serum level of vitamin D was 20.03±17.88 ng/ml;and significantly higher in the case group (24.58±20.75 ng/ml) than the control group (15.53±13.11ng/ml), especially in patients with stress and urgency urinary incontinence (both P<0.001).
Conclusion:The group with urinary incontinence due to PFD, especially the group with stress or urgency urinary incontinence had the highest vitamin D level, compared to the control group and other groups, although the mean age was significantly higher and educational level was lower in this group. These results could be due to the multi factorial nature of vitamin D level (varying based on nutrition, place of residence, etc.).
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