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Oct 2018, Vol 6, Issue 4
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Original Article
The Effect of Multivitamins Mineral and Q10 on Precancerous Lesions of the Cervix
Mitra Modarres Gilani1, Azam Sadat Mosavi1, Setare Akhavan1, Mehrangiz Zamani2, Mohammad Ali Mohsenpour3, Fatemeh Mohsenpour2, AzarPir Dehghan2, Danial Farhadi2, Fazezeh Torkzaban2
1Department of Obstetrics and Gynecology, Emam Hospital, Tehran University of Medical Sciences and Health Service, Tehran, Iran
2Department of Obstetrics and Gynecology, Fatemieh Hospital, Hamadan University of Medical Sciences and Health Services, Hamadan, Iran
3Department of Nutrition, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd, Iran


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Keywords : Dietary Supplement, Precancerous, Q10
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Abstract

Objectives: Invasive cervical cancer is one of the most fatal genital cancers in women which can be diagnosed by using Pap smear in precancerous stage. Various approaches are available for treating or preventing the progress of these precancerous lesions. The aim of this study ist o investigate the cytopathological and colposcopic response of precancerous lesions to multi-mineral and coenzyme Q10 supplements.

Materials and Methods:The present study is a randomized clinical trial which conducted on 120 participants with clinical complaint or abnormal Pap smear test. The intervention and control group received supplemental and placebo treatments for 3 months following by primarily Pap smear test. The Pap smear test was performed after treating and patients with abnormal results were screened by colposcopy. Data were analyzed through SPSS software and p-value was considered to be less than 0.05.

Results: The age frequency percentage in the intervention and control group was 40 % and 28.3 % in age range of 20-29, 26.7 % and 41.7 %  in age range of 30–39, and finally 33.3 % and 30 % for the age over 40 years, respectively (p= 0.19). The percentage of normalization in Pap smear test result was 83.3 and 53.3 % in the intervention and control group, respectively (p< 0.001).

Conclusion:  Form this study, it was found that short-term usage of multivitamin Mineral and Q10 supplement may decrease the risk of cervical cancer in women with abnormal Pap smear. However, studies with larger population and longer trial period are needed for further investigation.

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Articles by Modarres Gilani M
Articles by Sadat Mosavi A
Articles by Akhavan S
Articles by Zamani M
Articles by Ali Mohsenpour M
Articles by Mohsenpour F
Articles by Dehghan A
Articles by Farhadi D
Articles by Torkzaban F

PubMed

Articles by Azam Sadat Mosavi
Articles by Setare Akhavan
Articles by Mehrangiz Zamani
Articles by Fatemeh Mohsenpour
Articles by AzarPir Dehghan
Articles by Danial Farhadi
Articles by Fazezeh Torkzaban

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