|The Effect of Therapy for Tubal Ectopic Pregnancy on Subsequent Reproductive Capacity and The Frequency of Recurrence|
|Cordula Schippert, Sarah Gentemann, Jan-Simon Lanowski, Ismini Staboulidou, Philipp Soergel, Peter Hillemanns, Sudip Kundu|
|University Women's Hospital, Hanover Medical School, Hanover, Germany|
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Keywords : Ectopic tubal pregnancy, Frequency of recurrence,Sterility, Reproductive capacity, Recurrence rate
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Objective: Ectopic pregnancy (EP), whichis defined asthe implantation of anembryo outside the uterine cavity, occurswith notable frequency in the first trimester (especially between the sixtheninthweeks of gestation) and cancause severe intra-abdominal bleeding and death. Treatment options includesalpingotomy with tubal preservation, transampullar expression of the EP (“milking” of the tube), wedge excision with the chance for tubal reconstruction in a subsequent surgery and partial or complete salpingectomy. Drug treatment with Methotrexate (MTX) is also an option.
Materials and Methods: In this retrospective study, we analysed the data of patients who had been treated for an EP in the gynecological department of Hanover Medical School, Germany, between 2006 and 2013.
Results: We observed a pregnancy rate of 73.1%inthose who wanted to have children following EPtreatment, and 33 women (28.2%) became pregnant a second time. The birth rate after EPincreasedfrom 67.1% in the first subsequentpregnancyto more than 80% in the second. The frequency of recurrent EPwas 6.6% in the first pregnancy after surgery and 3% in the second.
Conclusions: These data are encouraging for EP patients, whohave a good chance to conceive, whetherspontaneously, after tubal reconstructive surgery or using in-vitro fertilisation(IVF).
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