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Apr 2018, Vol 6, Issue 2
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Original Article
The Effect of Fat Emulsion Intralipid 20% in Reproductive Outcome for Patients With Multiple Implantation Failure
Jawharah Al-Zebeidi, SaharLary, Dania Al-Jaroudi
Reproductive Endocrine and Infertility Medicine Department, King Fahad Medical City, Riyadh, Saudi Arabia, Riyadh, Saudi Arabia


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Keywords : Multiple implantation failure, Intralipid, Fat emulsion, Intracytoplasmic sperm injection, Pregnancy rate
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Abstract
Objective: The aim of this study is to evaluate the effect of fat emulsion Intralipid 20% on reproductive outcome of patients with multiple implantation failure (MIF).

Materials and methods: A retrospective study of 30 women with MIF who received Intralipid 20% within vitro fertilization ,intracytoplasmic sperm injection ( IVF-ICSI) treatment cycle was conducted in reproductive endocrine and infertility medicine department (REIMD) at Women Specialized Hospital, King Fahad Medical City (KFMC ), from January 2015 to December 2016.

Results: Thirteen of 30 women (43.3%) had positive pregnancy test and 17 (56.7%) did not. pregnancy rate show no statistical significant difference withthe use of long protocol in comparison to short antagonist protocol. Use of Intralipid 20% did not affect the embryo grading or yield higher number of frozen embryos.

Conclusion: Multiple implantation failure (MIF) is a challenging situation in reproductive medicine. Intralipid 20% might be an effective treatment for patients with multiple implantation failure.

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