|Uterine leiomyosarcoma: a case report|
|Forough Forghani1, Abolfazl Mehdizadeh Kashi2, Kambiz Sadegi3,4, Mania Kaveh2,1, Mehrangiz Ghafari5|
|1Department of obstetrics and gynecology, zabol university of medical science, zabol, Iran
2Endometriosis and Gynecological Disorder research center, Iran University of Medical Science, Tehran, Iran
3Pain research center, Iran University of Medical Science, Tehran, Iran
4Department of anesthesiology, zabol university of medical science, zabol, Iran5Department of pathology, zabol university of medical science, zabol, Iran
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Keywords : Uterine leiomyosarcoma, gynecologic oncologist
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Objective: Uterine leiomyosarcoma (LMS)is a rare cancer originated from smooth muscle lining the walls of the uterus. LMS is known as an aggressive tumor with high mortality and morbidityrates as compared to other uterine cancers, despite the disease stage at the time of diagnosis, ). In most cases, LMS has been misdiagnosed as benign uterine leiomyoma following hysterectomy or myomectomy.
Case Presentation: We present a 53-year-old G7 L7 woman who was referred to our clinic for abnormal uterine bleeding(AUB) for6 months. On physical examination, we found an abdominal mass that grew rapidlyin the last 4 months. The computed tomography (CT) scan results showed a heterogeneous mass extending from theepigastric regionto the pelvic area. Following an exploratory laparotomy, histopathology report confirmed the diagnosis of LMS. Her uterus, Fallopian tubes and ovaries were removed during a surgery, and she was referred to a gynecologic oncologist for possible chemotherapy.
Conclusions: We found that the surgery is the only treatment way for LMS; however, there is a small possibility to diagnose LMS before surgery,in patient with uncertain diagnosis and suspicious ofleiomyosarcoma , analysis of LDH and LDH3 levels along withdynamicgadolinium-diethylene-triaminepenta-acetic acid (Gd-DTPA) enhanced MRIisrecommended.
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