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Jan 2018, Vol 6, Issue 1
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Original Article
Can Follicular Fluid Anti-Mullerian Hormone Level be a Determinant For Pregnancy in Women Under 35 Years of Age?
Turabi Yilmaz1, Safak Tavukcuoglu1, Seval Tasdemir1, Semra Esenkaya1, Tulay Irez2
1Ferti-Jin In Vitro Fertilization Center, Istanbul, Turkey
2Biruni University, Medical Faculty, Department of Histology and Embryology, Istanbul, Turkey


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Keywords : Anti-Mullerian Hormone; Follicular Fluid; Oocyte; Embryo; Clinical Pregnancy; In-Vitro Fertilization
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Abstract
Objective: The failure of oocyte morphological assessment to predict in-Vitro fertilization (IVF) outcome has led the researchers to examine biochemical criteria of follicular fluid (FF). Anti-Mullerian hormone (AMH) an important marker of ovarian reserve is secreted by the granulosa cells. The aim of this study is to investigate the relationship of the FF (AMH) levels with oocyte, embryo quality, fertilization and clinical pregnancy.

Material and Methods: The FF (AMH) level of 61 patients (mean age: 33.72 ± 4.82 years; range: 21 to 42 years) were analyzed. The FF (AMH) levels were measured by the quantitative autoanalyzer with an electrochemiluminescence assay.

Results: The FF (AMH) levels in patients under 35 years of age were higher in women who were pregnant than non-pregnant women (p<0.01).

Conclusion: Our study result show that the FF (AMH) levels are correlated with oocyte and embryo quality and are the predictors of clinical pregnancy in patients younger than 35 years of age.

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