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Jan 2018, Vol 6, Issue 1
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Original Article
Comparison of the Effect of Melissa officinalis Capsule and Care Educational Programs on the Intensity of Physical, Mental and Social Symptoms of Premenstrual Syndrome in High School Female Students
Marzieh Akbarzadeh1, Zinab Moshfeghy2, Mansureh Dehghani3, Masoumeh Emamghoreishi4, Pouran Tavakoli5, Najaf Zare6
1Maternal–Fetal Medicine Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
2Community Based Psychiatric Care Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
3School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Pharmacology, School of Medicine, Shiraz University of Medical Sciences
5Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
6Infertility Research Center, School of Medicine, Department of Biostatistics, Shiraz University of Medical Sciences, Shiraz, Iran

IJWHR 2018; 6: 018-026
DOI: 10.15296/ijwhr.2018.05
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Keywords : Premenstrual syndrome, Melissa officinalis, Physical, Mental, Education, Student
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Abstract
Objectives: Premenstrual syndrome (PMS) is one of the psychosomatic problems related to women›s reproductive function, which is associated with emotional and mood symptoms such as anger, anxiety and irritability. The current study aimed to compare the effect of Melissa officinalis capsule and care educational programs on the intensity of physical, mental and social aspects of PMS in high school girls.

Materials and Methods: This study was a randomized, placebo-controlled trial which was conducted on 200 high school girls with PMS who were randomly allocated into 4 groups in Shiraz. The first group received 600 mg of M. officinalis essence daily from the first to the end day of their menstrual cycle for 3 consecutive cycles; the second and third groups received care educational program and placebo respectively, and the last one was the control group. The data were analyzed using paired t test and Repeated measures analysis of variance (ANOVA).

Results: The results of repeated measures ANOVA test revealed a significant reduction in 3 determined times, pre-intervention, one and 2 consecutive months after the intervention (P < 0.001), in the intensity of physical, psychological and social aspects of PMS symptoms, and this varied in different groups (P < 0.001). The extent of changes varied over time and in different groups, so, the control and placebo groups had the least symptom changes over the time

Conclusion: Melissa officinalis capsule and care educational programs were much more effective in reduction of the severity of physical, mental and social symptoms of PMS compared to the control and placebo groups.

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