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Jul 2017, Vol 5, Issue 3
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Original Article
Comparing The Outcomes And Side Effect of Administration of a Single Preoperative Dose of Vaghinal Misoprostol With Intraoperative Oxytocin Infusion ln Blood loss During Abdominal Myomectomy
Parvin Mostafa-Gharabaghi1, Sakineh Alizadeh1, Simin Atashkhoye1, Manizheh Sayyah-Melli1, Mehri Jafari-Shobeiri1, Elaheh Ouladsahebmadarek1, Laya Farzadi1, Yashar Hashemi Aghdam2
1Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2Islamic Azad University of Medical Sciences, Tabriz, Iran


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Keywords : Abdominal myomectomy, loss Misoprostol, Oxytocin
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Abstract
Objective: To Compare The Effectiveness of a Single Preoperative Dose of Misoprostol with Intraoperative Oxytocin Infusion in Abdominal Myomectomies.

Materials and Methods: Among patients undergoing abdominal myomectomies, an hour before the operation women in the misoprostol group (n=35) were given a single dose of vaginal misoprostol (400 μg); those in the oxytocin group (n=35) were given oxytocin (intravenous infusion 30 units in 1000 ml of normal saline solution during myomectomy).

Result(s): Blood loss, operation time, and need for blood transfusion were significantly reduced in the group given vaginal misoprostol. No difference observed among patients in term of the time of hospitalization and complications. The results of oxytocin in abdominal myomectomy showed no significant difference.

Conclusion: A single preoperative dose of misoprostol is a sample, reliable method for reducing intraoperative blood loss and need for postoperative blood transfusion after abdominal myomectomies.

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