|Synchronous Endometrial and Ovarian Cancer With Sigmoid Colon Metastasis One Year After Primary Surgery: A Case Report|
|Kadir Guzin1, Burcin Karamustafaoglu Balci1, Kemal Sandal1, Ahmet Gocmen1, Ozgur Ekinci2, Abdullah Aydin3, Meryem Yuvruk3|
|1Department of Obstetrics and Gynecology, Goztepe Training and Research Hospital, Medeniyet University, Istanbul, Turkey
2Department of General Surgery, Goztepe Training and Research Hospital, Medeniyet University, Istanbul, Turkey
3Department of Pathology, Goztepe Training and Research Hospital, Medeniyet University, Istanbul, Turkey
IJWHR 2015; 3: 220–222
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Keywords : Endometrial neoplasms, Neoplasm metastasis, Ovarian neoplasms, CA-125 antigen
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Introduction: We describe a patient who had ovarian and endometrial cancer which metastasized to sigmoid colon one year after surgery.
Case Presentation: A 53-year-old woman was admitted with the complaints of abdominal pain, abdominal distension and postmenopausal bleeding. Her transvaginal ultrasound scan revealed a cystic mass containing papillary projections with the dimensions of 6.5 × 5 × 4 cm on the right ovary. Level of (carbohydrate antigen) (CA) 125 was 223 IU. Dilation and curettage revealed endometrioid adenocarcinoma. Debulking surgerywas carried out. Histopathological diagnosis was grade 2 adenocarcinoma with squamous differentiation for endometrial cancer and grade 2 endometrioid adenocarcinoma with squamous and mucinous differentiation for ovarian cancer. The stage was 1A for endometrial cancer and 1A for ovarian cancer. 12 months after the operation CA 125 level was 112 IU. Positron emission tomography (PET) scan showed a small lesion (1.5×1.5 cm) in the pelvic cavity with increased fluorodeoxyglucose (FDG) uptake. Five months after the chemotherapy, CA 125 level elevated from 10 to 60 IU and subsequent magnetic resonance imaging (MRI) revealed a tumoral mass with the dimensions of 3×2.2 cm. A second laparotomy was performed and the metastasis was excited. The tumor was endometrioid adenocarcinoma with infiltration in the serosa and muscularis propria of sigmoid colon.
Conclusion: It is necessary to consider the presence of double cancer in the diagnosis and treatment of gynecological cancers.
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